Z700843
Sigma
Beginner’s Guide to Microarrays
| ISBN-10: | 1-4020-7472-7 |
| ISBN-13: | 978-1-4020-7472-1 |
Description
| General description | The manufacture, experimental design, and analysis of microarrays are not always straightforward, and researchers run into roadblocks that hinder progress. This book is directed to the core facility manager who produces, hybridizes, and scans arrays, and the research scientist who will be performing the analysis and interpreting the results. It provides a user friendly coverage and protocols for the technical steps and procedures involved in many facets of microarray technology, including: Coating glass slides; Designing oligonucleotide probes; Troubleshooting spotting problems; Normalizing background signal and controlling for systematic variance; Analyzing data with statistical procedures. |
Properties
| publication info | E. Blalock, ed., Kluwer Academic Publishers, 2003, 347 pp., hard cover |
Table Of Contents
| Table of Contents | Chapter 1. Slide Coating and DNA Immobilization Chemistries Chapter 2. Diagnostic Oligonucleotide Microarrays for Microbiology Chapter 3. Printing Technologies and Microarray Manufacturing Techniques: Making the Perfect Microarray Chapter 4. Arrays for the Masses:Setting Up a Microarray Core Facility Chapter 5. Microarray Data Normalization: The Art and Science of Overcoming Technical Variance to Maximize the Detection of Biological Variance Chapter 6. Experimental Design and Data Analysis Chapter 7. Microarray Experimental Design and Statistical Analysis Chapter 8. Strategies for Clustering, Classifying, Integrating, Standardizing and Visualizing Microarray Gene Expression Data Index |
